Basics of PET Imaging: Physics, Chemistry, and Regulations by Gopal B. Saha

By Gopal B. Saha

This revised version of fundamentals of puppy Imaging provides an extraordinary textual content at the fundamentals of puppy imaging expertise. unique writer, Dr. Gopal B. Saha, has up to date his prior bestselling paintings with concise chapters on puppy basics, including:

  • Basic physics
  • Instrumentation and knowledge acquisition
  • Production of puppy radionuclides
  • Performance features of puppy scanners
  • Regulatory and compensation issues

To maximize figuring out, and to aid technologists and citizens arrange for board assessments, chapters comprise pertinent uncomplicated technological know-how and equations in addition to pattern difficulties and perform questions. The awesome mix of Dr. Saha’s brevity and readability of content material once more makes this version an awesome reference publication for nuclear medication pros attracted to the fundamentals of puppy imaging.

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Extra info for Basics of PET Imaging: Physics, Chemistry, and Regulations

Example text

Each detector is connected in coincidence to as many as N/2 detectors, where N is the number of small detectors in the ring. So which two detectors detected a coincidence event within the time window must be determined. Pulses produced in PM tubes are used to determine the locations of the two detectors (Fig. 2). As in scintillation cameras, the position of each detector is estimated by a weighted centroid algorithm. 2. A schematic block detector is segmented into 8 × 8 elements, and four PM tubes are coupled to the block for pulse formation.

The light is then processed in the same manner as in the case of a solid detector, as discussed below. Both gas and liquid scintillation detectors have low detection efficiency and, therefore, are not used in PET technology. Interaction of radiations with solid scintillation detectors is the basis of radiation detection in PET technology. These solid detectors have the unique property of emitting scintillation or flashes of light after absorbing γ- or X-ray radiations. The light photons are converted to an electrical pulse or signal by a photomultiplier (PM) tube.

Because of the increased diagnostic accuracy offered by PET/CT, the worldwide market share of PET/CT is increasing exponentially, whereas that of the stand-alone PET scanners has dwindled to almost zero. Small Animal PET Scanner Drugs are commonly used in animal research prior to their clinical use in humans. The safety and effectiveness of a drug is initially established by studying its in vivo biodistribution and pharmacokinetics in animals. These animal studies using clinical PET systems are hindered by the relatively poor resolution of images offered by the scanner.

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