Antiepileptic Drugs to Treat Psychiatric Disorders (Medical by Susan L. McElroy, Paul E. Keck Jr., Robert M. Post

By Susan L. McElroy, Paul E. Keck Jr., Robert M. Post

A number of antiepileptic medicines (AEDs) now have regulatory symptoms for treating bipolar affliction. there's becoming proof that AEDs ordinarily have various invaluable psychotropic results. This ebook is the 1st complete, clinically orientated, reference at the use of AEDs to regard various psychiatric issues resembling temper, psychotic, nervousness, substance use, consuming, and character issues. Written by means of the top medical specialists, Antiepileptic medicinal drugs to regard Psychiatric issues: is equipped through psychiatric affliction for less complicated info amassing, and permits the healthcare professional to exploit the textual content as a stand on my own reference is the 1st accomplished reference ebook clinically oriented to using AEDs to regard psychiatric disorders—other books have all for drug mechanisms and drug interactions

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Extra info for Antiepileptic Drugs to Treat Psychiatric Disorders (Medical Psychiatry Series)

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39. Mula M, Trimble MR, Yuen A, et al. Psychiatric adverse events during levetiracetam therapy. Neurology 2003; 61(5):704–706. 40. Perucca E, Beghi E, Dulac O, et al. Assessing risk to benefit ratio in antiepileptic drug therapy. Epilepsy Res 2000; 41(2):107–139. 41. Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs. Lancet Neurol 2003; 2(8):473–481. 42. Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs.

31. Vajda FJ, Hitchcock A, Graham J, et al. Foetal malformations and seizure control: 52 months data of the Australian Pregnancy Registry. Eur J Neurol 2006; 13(6):645–654. 32. Tomson T, Battino D. Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium. Clin Pharmacokinet 2007; 46:209–219. 33. Perucca E, Berlowitz D, Birnbaum A, et al. Pharmacological and clinical aspects of antiepileptic drug use in the elderly. Epilepsy Res 2006; 68 (suppl 1):S49–S63.

Because of its potential hepatotoxic effects, valproate should be used cautiously or avoided in patients with hepatic disease, while carbamazepine should not be used in patients with preexisting dysfunction of the cardiac conduction system or cardiomyopathies (40). , valproate). Hence, AEDs are frequently involved in pharmacokinetic drug-drug interactions (41,42). In addition to changing the disposition of other drugs that patients may use, AEDs can be the substrate for interactions caused by other pharmaceutical agents.

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