Anatomy of neuropsychiatry : the new anatomy of the basal by Lennart Heimer; et al

By Lennart Heimer; et al

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Additional resources for Anatomy of neuropsychiatry : the new anatomy of the basal forebrain and its implications for neuropsychiatric illness

Sample text

Recent advances in experimental tract-tracing include sophisticated combinations of anatomical, physiological and histochemical techniques. Molecular biological methods can be used to study gene expression in anatomically and physiologically identified neurons. The difficult problem of studying connections in the human brain has received an unexpected boost from the development of diffusion tensor imaging (DTI), which is based on the tendency of water molecules to diffuse in the direction of myelinated fiber bundles.

Like the limbic system concept, the “emotional motor system” (or, for that matter, the very idea of a specific “emotional-motor” interface) has a popular appeal. As we will discuss at some length in Chapters 3–5, however, neither the description of a special “limbicmotor” interface nor the identification of a separate “emotional motor system” adequately addresses this multifaceted problem. Extended Amygdala The discovery of the extended amygdala (de Olmos and Ingram, 1972) and its elaboration as a functional-anatomical entity (Alheid and Heimer, 1988) is another subject of profound importance for understanding the organization of the forebrain.

Extended Amygdala The discovery of the extended amygdala (de Olmos and Ingram, 1972) and its elaboration as a functional-anatomical entity (Alheid and Heimer, 1988) is another subject of profound importance for understanding the organization of the forebrain. On the basis of a special silver staining technique, de Olmos and Ingram (1972) identified a prominent neuroanatomically and connectionally distinct continuum that includes the centromedial nucleus of the amygdala and bed nucleus of the stria terminalis and also occupies a substantial stretch of basal forebrain territory extending between these two structures and thus interconnecting them.

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